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Minimal mechanistic model of siRNA-dependent target RNA slicing by recombinant human Argonaute 2 protein

Argonaute (Ago) proteins are the key component of the RNA-induced silencing complex and mediate RNA interference (RNAi) in association with small RNAs. Although overall the mechanism of RNAi is well understood, many molecular details of this complex process are not. Here we report about in-depth ste...

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Detalhes bibliográficos
Main Authors: Deerberg, Andrea, Willkomm, Sarah, Restle, Tobias
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816469/
https://ncbi.nlm.nih.gov/pubmed/24101500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1217838110
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