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Structurally modulated codelivery of siRNA and Argonaute 2 for enhanced RNA interference

Small interfering RNA (siRNA) represents a promising class of inhibitors in both fundamental research and the clinic. Numerous delivery vehicles have been developed to facilitate siRNA delivery. Nevertheless, achieving highly potent RNA interference (RNAi) toward clinical translation requires effici...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Li, Jiahe, Wu, Connie, Wang, Wade, He, Yanpu, Elkayam, Elad, Joshua-Tor, Leemor, Hammond, Paula T.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866582/
https://ncbi.nlm.nih.gov/pubmed/29432194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1719565115
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