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ARGONAUTE 6 bridges transposable element mRNA-derived siRNAs to the establishment of DNA methylation
Transposable elements (TEs) generate mutations and chromosomal instability when active. To repress TE activity, eukaryotic cells evolved mechanisms to both degrade TE mRNAs into small interfering RNAs (siRNAs) and modify TE chromatin to epigenetically inhibit transcription. Since the populations of...
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| Publicado no: | EMBO J |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4291478/ https://ncbi.nlm.nih.gov/pubmed/25388951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201489499 |
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