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KIT GNNK splice variants: Expression in systemic mastocytosis and influence on the activating potential of the D816V mutation in mast cells

Stem cell factor–dependent KIT activation is an essential process for mast cell homeostasis. The two major splice variants of KIT differ by the presence or absence of four amino acids (GNNK) at the juxta-membrane region of the extracellular domain. We hypothesized that the expression pattern of thes...

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Main Authors: Chan, Eunice Ching, Bai, Yun, Bandara, Geethani, Simakova, Olga, Brittain, Erica, Scott, Linda, Dyer, Kimberly D., Klion, Amy D., Maric, Irina, Gilfillan, Alasdair M., Metcalfe, Dean D., Wilson, Todd M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816383/
https://ncbi.nlm.nih.gov/pubmed/23743299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2013.05.005
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