KIT GNNK splice variants: Expression in systemic mastocytosis and influence on the activating potential of the D816V mutation in mast cells

Stem cell factor–dependent KIT activation is an essential process for mast cell homeostasis. The two major splice variants of KIT differ by the presence or absence of four amino acids (GNNK) at the juxta-membrane region of the extracellular domain. We hypothesized that the expression pattern of thes...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Chan, Eunice Ching, Bai, Yun, Bandara, Geethani, Simakova, Olga, Brittain, Erica, Scott, Linda, Dyer, Kimberly D., Klion, Amy D., Maric, Irina, Gilfillan, Alasdair M., Metcalfe, Dean D., Wilson, Todd M.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816383/
https://ncbi.nlm.nih.gov/pubmed/23743299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2013.05.005
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki