Clonal analysis of NRAS activating mutations in KIT-D816V systemic mastocytosis

Cooperating genetic events are likely to contribute to the phenotypic diversity of KIT-D816V systemic mastocytosis. In this study, 44 patients with KIT-D816V systemic mastocytosis were evaluated for coexisting NRAS, KRAS, HRAS or MRAS mutations. Activating NRAS mutations were identified in 2 of 8 pa...

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Main Authors: Wilson, Todd M., Maric, Irina, Simakova, Olga, Bai, Yun, Ching Chan, Eunice, Olivares, Nicolas, Carter, Melody, Maric, Dragan, Robyn, Jamie, Metcalfe, Dean D.
Format: Artigo
Jezik:Inglês
Izdano: Ferrata Storti Foundation 2011
Teme:
Brief Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046279/
https://ncbi.nlm.nih.gov/pubmed/21134978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2010.031690
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