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Leptin Modulates Allograft Survival by Favoring a Th2 and a Regulatory Immune Profile
Leptin, an adipose-secreted hormone, links metabolism and immunity. Our aim was to determine whether leptin affects the alloimmune response. We used an allogeneic skin transplant model as a means to analyze the allograft immune response in Lep(ob/ob) and wild-type mice. Leptin deficiency results in...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3816358/ https://ncbi.nlm.nih.gov/pubmed/23016759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2012.04283.x |
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