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Leptin receptor signaling in T cells is required for Th17 differentiation

The hormone leptin plays a key role in energy homeostasis, and the absence of either leptin or its receptor (lepR) leads to severe obesity and metabolic disorders. To avoid indirect effects and to address the cell-intrinsic role of leptin signaling in the immune system, we conditionally targeted lep...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Reis, Bernardo S, Lee, Kihyun, Fanok, Melania H, Mascaraque, Cristina, Amoury, Manal, Cohn, Lillian, Rogoz, Aneta, Dallner, Olof S, Moraes-Vieira, Pedro M, Domingos, Ana I, Mucida, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433844/
https://ncbi.nlm.nih.gov/pubmed/25917102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402996
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