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Mutual expression of Runx3 and ThPOK regulates intestinal CD4(+) T cell immunity

The gut mucosa hosts large numbers of activated lymphocytes, exposed to stimuli from diet, microbiota and pathogens. Although CD4(+) T cells are crucial for defense, intestinal homeostasis precludes exaggerated response towards luminal contents, harmful or not. We investigated mechanisms used by CD4...

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Detalhes bibliográficos
Main Authors: Reis, Bernardo Sgarbi, Rogoz, Aneta, Costa-Pinto, Frederico Azevedo, Taniuchi, Ichiro, Mucida, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804366/
https://ncbi.nlm.nih.gov/pubmed/23334789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2518
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