Twist2 promotes CD8(+) T-cell differentiation by repressing ThPOK expression

CD4/CD8 T-cell lineage differentiation is a key process in immune system development; however, a defined regulator(s) that converts the signal from T-cell receptor and co-receptor complexes into lineage differentiation remains unclear. Here, we show that Twist2 is a critical factor in CD4/CD8 thymoc...

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Udgivet i:Cell Death Differ
Main Authors: Hwang, Sunsook, Lee, Changjin, Park, Kyungsoo, Oh, Sangwook, Jeon, Shin, Kang, Byeonggeun, Kim, Yehyun, Oh, Jaehak, Jeon, Sung Ho, Satake, Masanobu, Taniuchi, Ichiro, Lee, Ho, Seong, Rho Hyun
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7560870/
https://ncbi.nlm.nih.gov/pubmed/32424141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-0560-x
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