Leptin deficiency impairs maturation of dendritic cells and enhances induction of regulatory T and Th17 cells

Leptin is an adipose-secreted hormone that plays an important role in both metabolism and immunity. Leptin has been shown to induce Th1-cell polarization and inhibit Th2-cell responses. Additionally, leptin induces Th17-cell responses, inhibits regulatory T (Treg) cells and modulates autoimmune dise...

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Moraes-Vieira, Pedro M.M., Larocca, Rafael A., Bassi, Enio J., Peron, Jean Pierre S., Andrade-Oliveira, Vinícius, Wasinski, Frederick, Araujo, Ronaldo, Thornley, Thomas, Quintana, Francisco J., Basso, Alexandre S., Strom, Terry B., Câmara, Niels O.S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973395/
https://ncbi.nlm.nih.gov/pubmed/24271843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201343592
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