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FUNCTIONAL EVALUATION OF AUTISM-ASSOCIATED MUTATIONS IN NHE9

NHE9 (SLC9A9) is an endosomal cation/proton antiporter with orthologs in yeast and bacteria. Rare, missense substitutions in NHE9 are genetically linked with autism, but have not been functionally evaluated. Here we use evolutionary conservation analysis to build a model-structure of NHE9 based on t...

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Detalhes bibliográficos
Main Authors: Kondapalli, Kalyan C., Hack, Anniesha, Schushan, Maya, Landau, Meytal, Ben-Tal, Nir, Rao, Rajini
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815575/
https://ncbi.nlm.nih.gov/pubmed/24065030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3510
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