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A structural model of the copper ATPase ATP7B to facilitate analysis of Wilson disease-causing mutations and studies of the transport mechanism
The copper-transporting ATPase ATP7B has an essential role in human physiology, particularly for the liver and brain function. Inactivation of ATP7B is associated with a severe hepatoneurologic disorder, Wilson disease (WD). Hundreds of WD related mutations have been identified in ATP7B to date. The...
Gorde:
| Argitaratua izan da: | Metallomics |
|---|---|
| Egile Nagusiak: | , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2012
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6365107/ https://ncbi.nlm.nih.gov/pubmed/22692182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2mt20025b |
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