Wordt geladen...
Spartin Regulates Synaptic Growth and Neuronal Survival by Inhibiting BMP-Mediated Microtubule Stabilization
Troyer syndrome is a hereditary spastic paraplegia caused by human spartin (SPG20) gene mutations. We have generated a Drosophila disease model showing that Spartin functions presynaptically with endocytic adaptor Eps15 to regulate synaptic growth and function. Spartin inhibits bone morphogenetic pr...
Bewaard in:
| Hoofdauteurs: | , , , , , , , , , , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2013
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3815429/ https://ncbi.nlm.nih.gov/pubmed/23439121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.12.015 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|