BMP-dependent synaptic development requires Abi-Abl-Rac signaling of BMP receptor macropinocytosis

Retrograde BMP trans-synaptic signaling is essential for synaptic development. Despite the importance of endocytosis-regulated BMP receptor (BMPR) control of this developmental signaling, the mechanism remains unknown. Here, we provide evidence that Abelson interactor (Abi), a substrate for Abl kina...

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Publicado no:Nat Commun
Main Authors: Kim, Najin, Kim, Sungdae, Nahm, Minyeop, Kopke, Danielle, Kim, Joohyung, Cho, Eunsang, Lee, Min-Jung, Lee, Mihye, Kim, Seung Hyun, Broadie, Kendal, Lee, Seungbok
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368546/
https://ncbi.nlm.nih.gov/pubmed/30737382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08533-2
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