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The Rap activator Gef26 regulates synaptic growth and neuronal survival via inhibition of BMP signaling

In Drosophila, precise regulation of BMP signaling is essential for normal synaptic growth at the larval neuromuscular junction (NMJ) and neuronal survival in the adult brain. However, the molecular mechanisms underlying fine-tuning of BMP signaling in neurons remain poorly understood. We show that...

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Detalhes bibliográficos
Publicado no:Mol Brain
Main Authors: Heo, Keunjung, Nahm, Minyeop, Lee, Min-Jung, Kim, Young-Eun, Ki, Chang-Seok, Kim, Seung Hyun, Lee, Seungbok
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745669/
https://ncbi.nlm.nih.gov/pubmed/29282074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-017-0342-7
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