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The Rap activator Gef26 regulates synaptic growth and neuronal survival via inhibition of BMP signaling

In Drosophila, precise regulation of BMP signaling is essential for normal synaptic growth at the larval neuromuscular junction (NMJ) and neuronal survival in the adult brain. However, the molecular mechanisms underlying fine-tuning of BMP signaling in neurons remain poorly understood. We show that...

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Publicat a:Mol Brain
Autors principals: Heo, Keunjung, Nahm, Minyeop, Lee, Min-Jung, Kim, Young-Eun, Ki, Chang-Seok, Kim, Seung Hyun, Lee, Seungbok
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745669/
https://ncbi.nlm.nih.gov/pubmed/29282074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-017-0342-7
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