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Probing the Coordination Environment of the Human Copper Chaperone HAH1: Characterization of Hg(II)-Bridged Homodimeric Species in Solution

While metal ion homeostasis in cells is often mediated through metallochaperones, there are opportunities for toxic metals to be sequestered through the existing transport apparatus. Proper trafficking of Cu(I) in human cells is partially achieved through complexation by HAH1, the human metallochape...

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Detalhes bibliográficos
Main Authors: Łuczkowski, Marek, Zeider, Brian A., Hinz, Alia V. H., Stachura, Monika, Chakraborty, Saumen, Hemmingsen, Lars, Huffman, David L., Pecoraro, Vincent L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814132/
https://ncbi.nlm.nih.gov/pubmed/23677531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201204184
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