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Structure of human Wilson protein domains 5 and 6 and their interplay with domain 4 and the copper chaperone HAH1 in copper uptake

Human Wilson protein is a copper-transporting ATPase located in the secretory pathway possessing six N-terminal metal-binding domains. Here we focus on the function of the metal-binding domains closest to the vesicular portion of the copper pump, i.e., domain 4 (WLN4), and a construct of domains 5 a...

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Bibliografiset tiedot
Päätekijät: Achila, David, Banci, Lucia, Bertini, Ivano, Bunce, Jennifer, Ciofi-Baffoni, Simone, Huffman, David L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2006
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458641/
https://ncbi.nlm.nih.gov/pubmed/16571664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504472103
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