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Mitochondrial copper(I) transfer from Cox17 to Sco1 is coupled to electron transfer

The human protein Cox17 contains three pairs of cysteines. In the mitochondrial intermembrane space (IMS) it exists in a partially oxidized form with two S–S bonds and two reduced cysteines (HCox17(2S-S)). HCox17(2S-S) is involved in copper transfer to the human cochaperones Sco1 and Cox11, which ar...

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Autores principales: Banci, Lucia, Bertini, Ivano, Ciofi-Baffoni, Simone, Hadjiloi, Theodoros, Martinelli, Manuele, Palumaa, Peep
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2383975/
https://ncbi.nlm.nih.gov/pubmed/18458339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800019105
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