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A hint for the function of human Sco1 from different structures

The solution structures of apo, Cu(I), and Ni(II) human Sco1 have been determined. The protein passes from an open and conformationally mobile state to a closed and rigid conformation upon metal binding as shown by electrospray ionization MS and NMR data. The metal ligands of Cu(I) are two Cys resid...

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Detalhes bibliográficos
Main Authors: Banci, Lucia, Bertini, Ivano, Calderone, Vito, Ciofi-Baffoni, Simone, Mangani, Stefano, Martinelli, Manuele, Palumaa, Peep, Wang, Shenlin
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482625/
https://ncbi.nlm.nih.gov/pubmed/16735468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0601375103
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