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Direct Observation of Nanosecond Water Exchange Dynamics at a Protein Metal Site

Nanosecond ligand exchange dynamics at metal sites within proteins is essential in catalysis, metal ion transport, and regulatory metallobiochemistry. Herein we present direct observation of the exchange dynamics of water at a Cd(2+) binding site within two de novo designed metalloprotein constructs...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Stachura, Monika, Chakraborty, Saumen, Gottberg, Alexander, Ruckthong, Leela, Pecoraro, Vincent L., Hemmingsen, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372835/
https://ncbi.nlm.nih.gov/pubmed/27973778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b11525
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