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Direct Observation of Nanosecond Water Exchange Dynamics at a Protein Metal Site

Nanosecond ligand exchange dynamics at metal sites within proteins is essential in catalysis, metal ion transport, and regulatory metallobiochemistry. Herein we present direct observation of the exchange dynamics of water at a Cd(2+) binding site within two de novo designed metalloprotein constructs...

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Podrobná bibliografie
Vydáno v:J Am Chem Soc
Hlavní autoři: Stachura, Monika, Chakraborty, Saumen, Gottberg, Alexander, Ruckthong, Leela, Pecoraro, Vincent L., Hemmingsen, Lars
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372835/
https://ncbi.nlm.nih.gov/pubmed/27973778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b11525
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