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Distinct roles for ATP binding and hydrolysis at individual subunits of an archaeal clamp loader

Circular clamps are utilised by replicative polymerases to enhance processivity. The topological problem of loading a toroidal clamp onto DNA is overcome by ATP-dependent clamp loader complexes. Different organisms use related protein machines to load clamps, but the mechanisms by which they utilise...

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Détails bibliographiques
Auteurs principaux: Seybert, Anja, Wigley, Dale B
Format: Artigo
Langue:Inglês
Publié: 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC381406/
https://ncbi.nlm.nih.gov/pubmed/15014449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600130
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