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Distinct roles for ATP binding and hydrolysis at individual subunits of an archaeal clamp loader
Circular clamps are utilised by replicative polymerases to enhance processivity. The topological problem of loading a toroidal clamp onto DNA is overcome by ATP-dependent clamp loader complexes. Different organisms use related protein machines to load clamps, but the mechanisms by which they utilise...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC381406/ https://ncbi.nlm.nih.gov/pubmed/15014449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600130 |
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