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Dual Functions, Clamp Opening and Primer-Template Recognition, Define a Key Clamp Loader Subunit
Clamp loader proteins catalyze assembly of circular sliding clamps on DNA to enable processive DNA replication. During the reaction, the clamp loader binds primer-template DNA and positions it in the center of a clamp to form a topological link between the two. Clamp loaders are multi-protein comple...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2849281/ https://ncbi.nlm.nih.gov/pubmed/15364574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2004.07.097 |
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