Dual Functions, Clamp Opening and Primer-Template Recognition, Define a Key Clamp Loader Subunit

Clamp loader proteins catalyze assembly of circular sliding clamps on DNA to enable processive DNA replication. During the reaction, the clamp loader binds primer-template DNA and positions it in the center of a clamp to form a topological link between the two. Clamp loaders are multi-protein comple...

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Huvudupphovsmän: Coman, Maria Magdalena, Jin, Mi, Ceapa, Razvan, Finkelstein, Jeff, O'Donnell, Michael, Chait, Brian T., Hingorani, Manju M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2004
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849281/
https://ncbi.nlm.nih.gov/pubmed/15364574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2004.07.097
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