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Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis

Autodigestion of the pancreas by its own prematurely activated digestive proteases is thought to be an important event in the onset of acute pancreatitis. The mechanism responsible for the intrapancreatic activation of digestive zymogens is unknown, but a recent hypothesis predicts that a redistribu...

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Detalhes bibliográficos
Main Authors: Halangk, Walter, Lerch, Markus M., Brandt-Nedelev, Barbara, Roth, Wera, Ruthenbuerger, Manuel, Reinheckel, Thomas, Domschke, Wolfram, Lippert, Hans, Peters, Christoph, Deussing, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC381392/
https://ncbi.nlm.nih.gov/pubmed/10995788
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