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Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis

Autodigestion of the pancreas by its own prematurely activated digestive proteases is thought to be an important event in the onset of acute pancreatitis. The mechanism responsible for the intrapancreatic activation of digestive zymogens is unknown, but a recent hypothesis predicts that a redistribu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Halangk, Walter, Lerch, Markus M., Brandt-Nedelev, Barbara, Roth, Wera, Ruthenbuerger, Manuel, Reinheckel, Thomas, Domschke, Wolfram, Lippert, Hans, Peters, Christoph, Deussing, Jan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2000
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC381392/
https://ncbi.nlm.nih.gov/pubmed/10995788
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