The Tyrosine Kinase Receptor ROR1 Is Constitutively Phosphorylated in Chronic Lymphocytic Leukemia (CLL) Cells

Phosphorylation of receptor tyrosine kinases (RTKs) has a key role in cellular functions contributing to the malignant phenotype of tumor cells. We and others have previously demonstrated that RTK ROR1 is overexpressed in chronic lymphocytic leukemia (CLL). Silencing siRNA downregulated ROR1 and ind...

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Detalhes bibliográficos
Main Authors: Hojjat-Farsangi, Mohammad, Khan, Abdul Salam, Daneshmanesh, Amir Hossein, Moshfegh, Ali, Sandin, Åsa, Mansouri, Ladan, Palma, Marzia, Lundin, Jeanette, Österborg, Anders, Mellstedt, Håkan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3813472/
https://ncbi.nlm.nih.gov/pubmed/24205204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078339
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