The Tyrosine Kinase Receptor ROR1 Is Constitutively Phosphorylated in Chronic Lymphocytic Leukemia (CLL) Cells

Phosphorylation of receptor tyrosine kinases (RTKs) has a key role in cellular functions contributing to the malignant phenotype of tumor cells. We and others have previously demonstrated that RTK ROR1 is overexpressed in chronic lymphocytic leukemia (CLL). Silencing siRNA downregulated ROR1 and ind...

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Hlavní autoři: Hojjat-Farsangi, Mohammad, Khan, Abdul Salam, Daneshmanesh, Amir Hossein, Moshfegh, Ali, Sandin, Åsa, Mansouri, Ladan, Palma, Marzia, Lundin, Jeanette, Österborg, Anders, Mellstedt, Håkan
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3813472/
https://ncbi.nlm.nih.gov/pubmed/24205204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078339
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