Inhibition of the Receptor Tyrosine Kinase ROR1 by Anti-ROR1 Monoclonal Antibodies and siRNA Induced Apoptosis of Melanoma Cells

The receptor tyrosine kinase (RTK) ROR1 is overexpressed and of importance for the survival of various malignancies, including lung adenocarcinoma, breast cancer and chronic lymphocytic leukemia (CLL). There is limited information however on ROR1 in melanoma. In the present study we analysed in seve...

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Main Authors: Hojjat-Farsangi, Mohammad, Ghaemimanesh, Fatemeh, Daneshmanesh, Amir Hossein, Bayat, Ali-Ahmad, Mahmoudian, Jafar, Jeddi-Tehrani, Mahmood, Rabbani, Hodjatallah, Mellstedt, Hakan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620154/
https://ncbi.nlm.nih.gov/pubmed/23593420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061167
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