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A point mutation in the human Slo1 channel that impairs its sensitivity to omega-3 docosahexaenoic acid
Long-chain polyunsaturated omega-3 fatty acids such as docosahexaenoic acid (DHA) at nanomolar concentrations reversibly activate human large-conductance Ca(2+)- and voltage-gated K(+) (Slo1 BK) channels containing auxiliary β1 or β4 subunits in cell-free patches. Here we examined the action of DHA...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3813383/ https://ncbi.nlm.nih.gov/pubmed/24127525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201311061 |
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