Llwytho...

Transmembrane helix heterodimerization in lipid bilayers: probing the energetics behind autosomal dominant growth disorders

Here we show that the energetics of TM helix heterodimer formation can be characterized in liposomes using FRET. We present the theory and the protocol for measuring the free energy of heterodimerization, and the total (hetero and homo-dimeric) dimer fraction. We use the presented methodology to det...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Merzlyakov, Mikhail, You, Min, Li, Edwin, Hristova, Kalina
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2006
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812923/
https://ncbi.nlm.nih.gov/pubmed/16500676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.01.086
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