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T Cell Receptor “Inside-Out” Pathway via Signaling Module SKAP1-RapL Regulates T Cell Motility and Interactions in Lymph Nodes
Although essential for T cell function, the identity of the T cell receptor “inside-out” pathway for lymphocyte function-associated antigen 1 (LFA-1) adhesion has proved elusive. Here, we define the “inside-out” pathway mediated by N-terminal SKAP1 (SKAP-55) domain binding to the C-terminal SARAH do...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3812847/ https://ncbi.nlm.nih.gov/pubmed/20346707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.03.007 |
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