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Immune adaptor protein SKAP1 (SKAP-55) forms homodimers as mediated by the N-terminal region

OBJECTIVE: Immune cell adaptor protein SKAP1 couples the antigen-receptor (TCR/CD3) with the activation of LFA-1 adhesion in T-cells. Previous work by ourselves and others have shown that SKAP1 can directly bind to other adaptors such as ADAP and RapL. However, it has been unclear whether SKAP1 can...

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Библиографические подробности
Опубликовано в: :BMC Res Notes
Главные авторы: Raab, Monika, Strebhardt, Klaus, Rudd, Christopher E.
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282339/
https://ncbi.nlm.nih.gov/pubmed/30522503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-018-3976-3
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