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Osteoblast-targeted Suppression of PPARγ Increases Osteogenesis through Activation of mTOR Signaling
Nuclear receptor peroxisome proliferator-activated receptor gamma (PPARγ) is an essential transcription factor for adipocyte differentiation. In mesenchymal stem cells, PPARγ has been assumed to play a negative role in osteoblastic differentiation, by working in an adipogenesis dependent manner, due...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3812401/ https://ncbi.nlm.nih.gov/pubmed/23766271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1455 |
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