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Ghrelin promotes hepatic lipogenesis by activation of mTOR-PPARγ signaling pathway

Although ghrelin has been demonstrated to stimulate energy intake and storage through a central mechanism, its effect on hepatic lipid metabolism remains largely uncharacterized. Ghrelin receptor antagonism or gene deletion significantly decreased obesity-associated hepatic steatosis by suppression...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Li, Ziru, Xu, Geyang, Qin, Yan, Zhang, Chao, Tang, Hong, Yin, Yue, Xiang, Xinxin, Li, Yin, Zhao, Jing, Mulholland, Michael, Zhang, Weizhen
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246976/
https://ncbi.nlm.nih.gov/pubmed/25157160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1411571111
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