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mTOR activation protects liver from ischemia/reperfusion-induced injury through NF-κB pathway

Hepatic steatosis renders liver more vulnerable to ischemia/reperfusion injury (IRI), which commonly occurs in transplantation, trauma, and liver resection. The underlying mechanism is not fully characterized. We aimed to clarify the role of mechanistic target of rapamycin (mTOR) signaling in hepati...

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Publicado en:FASEB J
Autores principales: Li, Ziru, Zhang, Jing, Mulholland, Michael, Zhang, Weizhen
Formato: Artigo
Lenguaje:Inglês
Publicado: Federation of American Societies for Experimental Biology 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471519/
https://ncbi.nlm.nih.gov/pubmed/28356345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201601278R
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