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Bortezomib Resistance Can Be Reversed by Induced Expression of Plasma Cell Maturation Markers in a Mouse In Vitro Model of Multiple Myeloma

Multiple myeloma (MM), the second most common hematopoietic malignancy, remains an incurable plasma cell (PC) neoplasm. While the proteasome inhibitor, bortezomib (Bz) has increased patient survival, resistance represents a major treatment obstacle as most patients ultimately relapse becoming refrac...

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Detalles Bibliográficos
Main Authors: Stessman, Holly A. F., Mansoor, Aatif, Zhan, Fenghuang, Linden, Michael A., Van Ness, Brian, Baughn, Linda B.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812176/
https://ncbi.nlm.nih.gov/pubmed/24204892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077608
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