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Phenotypic and functional characterization of a bortezomib resistant multiple myeloma cell line by flow and mass cytometry

Multiple myeloma (MM) is an incurable malignant plasma cell neoplasm. Proteasome inhibitors including Bortezomib (Bz) are used to treat MM, and treatment failure due to drug resistance occurs. Bz sensitive and resistant MM cells have distinct immunophenotypic signatures that correlate with clinical...

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Detalhes bibliográficos
Publicado no:Leuk Lymphoma
Main Authors: Baughn, Linda B., Sachs, Zohar, Noble-Orcutt, Klara, Mitra, Amit, Van Ness, Brian G., Linden, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5504883/
https://ncbi.nlm.nih.gov/pubmed/27981867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10428194.2016.1266621
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