Essential Role for Dnmt1 in the Prevention and Maintenance of MYC-Induced T-Cell Lymphomas

DNA cytosine methylation is an epigenetic modification involved in the transcriptional repression of genes controlling a variety of physiological processes, including hematopoiesis. DNA methyltransferase 1 (Dnmt1) is a key enzyme involved in the somatic inheritance of DNA methylation and thus plays...

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Autors principals: Peters, Staci L., Hlady, Ryan A., Opavska, Jana, Klinkebiel, David, Novakova, Slavomira, Smith, Lynette M., Lewis, Robert E., Karpf, Adam R., Simpson, Melanie A., Wu, Lizhao, Opavsky, Rene
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811897/
https://ncbi.nlm.nih.gov/pubmed/24001767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00776-13
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