Short-Lived Effector CD8 T Cells Induced by Genetically Attenuated Malaria Parasite Vaccination Express CD11c

Vaccination with a single dose of genetically attenuated malaria parasites can induce sterile protection against sporozoite challenge in the rodent Plasmodium yoelii model. Protection is dependent on CD8(+) T cells, involves perforin and gamma interferon (IFN-γ), and is correlated with the expansion...

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Autori principali: Cooney, Laura A., Gupta, Megha, Thomas, Sunil, Mikolajczak, Sebastian, Choi, Kimberly Y., Gibson, Claire, Jang, Ihn K., Danziger, Sam, Aitchison, John, Gardner, Malcolm J., Kappe, Stefan H. I., Wang, Ruobing
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2013
Soggetti:
Microbial Immunity and Vaccines
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811835/
https://ncbi.nlm.nih.gov/pubmed/23980113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00871-13
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