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In Vivo Physiological and Transcriptional Profiling Reveals Host Responses to Clostridium difficile Toxin A and Toxin B

Toxin A (TcdA) and toxin B (TcdB) of Clostridium difficile cause gross pathological changes (e.g., inflammation, secretion, and diarrhea) in the infected host, yet the molecular and cellular pathways leading to observed host responses are poorly understood. To address this gap, we evaluated the effe...

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Detalhes bibliográficos
Main Authors: D'Auria, Kevin M., Kolling, Glynis L., Donato, Gina M., Warren, Cirle A., Gray, Mary C., Hewlett, Erik L., Papin, Jason A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811747/
https://ncbi.nlm.nih.gov/pubmed/23897615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00869-13
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