Role of Leptin-Mediated Colonic Inflammation in Defense against Clostridium difficile Colitis

The role of leptin in the mucosal immune response to Clostridium difficile colitis, a leading cause of nosocomial infection, was studied in humans and in a murine model. Previously, a mutation in the receptor for leptin (LEPR) was shown to be associated with susceptibility to infectious colitis and...

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Bibliographic Details
Main Authors: Madan, Rajat, Guo, Xiaoti, Naylor, Caitlin, Buonomo, Erica L., Mackay, Donald, Noor, Zannatun, Concannon, Patrick, Scully, Kenneth W., Pramoonjago, Patcharin, Kolling, Glynis L., Warren, Cirle A., Duggal, Priya, Petri, William A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911837/
https://ncbi.nlm.nih.gov/pubmed/24166957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00972-13
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