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Glucosylation Drives the Innate Inflammatory Response to Clostridium difficile Toxin A

Clostridium difficile is a major, life-threatening hospital-acquired pathogen that causes mild to severe colitis in infected individuals. The tissue destruction and inflammation which characterize C. difficile infection (CDI) are primarily due to the Rho-glucosylating toxins A and B. These toxins ca...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Cowardin, Carrie A., Jackman, Brianna M., Noor, Zannatun, Burgess, Stacey L., Feig, Andrew L., Petri, William A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962640/
https://ncbi.nlm.nih.gov/pubmed/27271747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00327-16
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