Maspin acts at the cell membrane to inhibit invasion and motility of mammary and prostatic cancer cells.

Maspin, a novel serine protease inhibitor (serpin), inhibits tumor invasion and metastasis of mammary carcinoma. We show here that recombinant maspin protein blocks the motility of these carcinoma cells in culture over 12 h, as demonstrated by time-lapse video microscopy. Lamellopodia are withdrawn...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Sheng, S, Carey, J, Seftor, E A, Dias, L, Hendrix, M J, Sager, R
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1996
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38116/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8876194/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.21.11669
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