Maspin acts at the cell membrane to inhibit invasion and motility of mammary and prostatic cancer cells.
Maspin, a novel serine protease inhibitor (serpin), inhibits tumor invasion and metastasis of mammary carcinoma. We show here that recombinant maspin protein blocks the motility of these carcinoma cells in culture over 12 h, as demonstrated by time-lapse video microscopy. Lamellopodia are withdrawn...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
1996
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38116/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8876194/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.21.11669 |
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