Maspin acts at the cell membrane to inhibit invasion and motility of mammary and prostatic cancer cells.

Maspin, a novel serine protease inhibitor (serpin), inhibits tumor invasion and metastasis of mammary carcinoma. We show here that recombinant maspin protein blocks the motility of these carcinoma cells in culture over 12 h, as demonstrated by time-lapse video microscopy. Lamellopodia are withdrawn...

Fuld beskrivelse

Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Sheng, S, Carey, J, Seftor, E A, Dias, L, Hendrix, M J, Sager, R
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1996
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38116/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8876194/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.21.11669
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!