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In Vitro Characterization of GSK2485852, a Novel Hepatitis C Virus Polymerase Inhibitor
GSK2485852 (referred to here as GSK5852) is a hepatitis C virus (HCV) NS5B polymerase inhibitor with 50% effective concentrations (EC(50)s) in the low nanomolar range in the genotype 1 and 2 subgenomic replicon system as well as the infectious HCV cell culture system. We have characterized the antiv...
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| 主要な著者: | , , , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2013
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3811320/ https://ncbi.nlm.nih.gov/pubmed/23939896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00874-13 |
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