Therapeutically Attenuating Neutrophil Recruitment With a CXCR2 Antagonist in Combination With Oseltamivir Ameliorates Influenza-Induced Lung Injury and Disease

Mice were infected with influenza and treated with a CXCR2 antagonist in combination with antiviral or antiviral alone starting 4 days postinfection. Neutrophil recruitment to the lung was reduced, and improvements in health outcomes and lung consolidation were observed in combination-treated mice w...

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Detalhes bibliográficos
Publicado no:Open Forum Infect Dis
Main Authors: Washburn, Michael L, Crosby, Renae, Remlinger, Katja, Wang, Feng, Creech, Donald
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483135/
https://ncbi.nlm.nih.gov/pubmed/31041337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz106
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