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CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrow

Neutrophils are a major component of the innate immune response. Their homeostasis is maintained, in part, by the regulated release of neutrophils from the bone marrow. Constitutive expression of the chemokine CXCL12 by bone marrow stromal cells provides a key retention signal for neutrophils in the...

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Autors principals: Eash, Kyle J., Greenbaum, Adam M., Gopalan, Priya K., Link, Daniel C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898597/
https://ncbi.nlm.nih.gov/pubmed/20516641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI41649
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